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To analyze the impact of IKK2 inhibitor VIII (HY-13060, Medchem Specific, Monmouth Junction, NJ) on OA growth, MLI surgical procedures ended up carried out in twelve-7 days-aged C57BL/six WT mice. The mice ended up injected with IKK2 inhibitor VIII (two mg/kg, IP) every single alternate working day for 5 weeks. OARSI scoring was performed by blin